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Gene set: tob1Pathway (C2:PATH:0303)
Standard nametob1Pathway
Systematic nameC2:PATH:0303
Brief descriptionTGF-beta signaling activates SMADs, which interact with intracellular Tob to maintain unstimulated T cells by repressing IL-2 expression.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_tob1Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

21 genes, 21 accessions (Toggle view)

GeneTitleLinks
CD3ECD3E antigen, epsilon polypeptide (TiT3 complex)Source|GeneCards
TRB@T cell receptor beta locusSource|GeneCards
IL2interleukin 2Source|GeneCards
CD3ZCD3Z antigen, zeta polypeptide (TiT3 complex)Source|GeneCards
TGFB2transforming growth factor, beta 2Source|GeneCards
IFNGinterferon, gammaSource|GeneCards
TRA@T cell receptor alpha locusSource|GeneCards
IL4interleukin 4Source|GeneCards
TGFB3transforming growth factor, beta 3Source|GeneCards
TGFBR2transforming growth factor, beta receptor II (70/80kDa)Source|GeneCards
TOB2transducer of ERBB2, 2Source|GeneCards
CD3GCD3G antigen, gamma polypeptide (TiT3 complex)Source|GeneCards
TOB1transducer of ERBB2, 1Source|GeneCards
TGFBR3transforming growth factor, beta receptor III (betaglycan, 300kDa)Source|GeneCards
CD3DCD3D antigen, delta polypeptide (TiT3 complex)Source|GeneCards
TGFBR1transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)Source|GeneCards
IL2RAinterleukin 2 receptor, alphaSource|GeneCards
TGFB1transforming growth factor, beta 1 (Camurati-Engelmann disease)Source|GeneCards
CD28CD28 antigen (Tp44)Source|GeneCards