XX
 XX
 XX
 FA ATF3
 XX
 SY activating transcription
factor 3; LRG-21.
 XX
 OS mouse, Mus musculus
 OC eukaryota;
animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;

OC eutheria; rodentia; myomorpha; muridae; murinae
 XX

XX
 CL C0008; bZIP.
 XX
 SZ 181 AA; 20.7 kDa (calc)

XX
 XX
 SC translated from EMBL #U19118
 XX
 FT 84
148 PF00170; bZIP.
 FT 84 148 SM00338; BRLZ.
 FT 88 110
basic region.
 FT 114 142 leucine zipper.
 XX
 CP (cell
lines:) RAW 264.7, peritoneal macrophages [2]
 XX
 FF induced
by lipopolysaccharide (LPS), interferon-gamma and interleukin-4
[2];
 FF plays an important role in macrophage activation [2];

FF induced by stress signals in the pancreas and cultured isled
cells [1];
 FF transgenic mice show growth retardation, altered
expression of genes
 FF encoding gluconeogenic enzymes, abnormal
endocrine pancreas and disturbance
 FF in glucose homeostasis
[1];
 XX
 XX
 XX
 RN [1]; RE0017060.
 RX MEDLINE;
21369907.
 RA Allen-Jennings A. E., Hartman M. G., Kociba G.
J., Hai T.
 RT The roles of ATF3 in glucose homeostasis. A
transgenic mouse model with
 RT liver dysfunction and defects
in endocrine pancreas
 RL J. Biol. Chem. 276:29507-29514 (2001).

RN [2]; RE0017056.
 RX MEDLINE; 97119300.
 RA Drysdale B.
E., Howard D. L., Johnson R. J.
 RT Identification of a lipopolysaccharide
inducible transcription factor in
 RT murine macrophages

RL Mol. Immunol. 33:989-998 (1996).
 XX