XX
 XX
 XX
 FA Sox-5
 XX
 SY SRY-related HMG-box
gene 5.
 XX
 OS mouse, Mus musculus
 OC eukaryota; animalia;
metazoa; chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria;
rodentia; myomorpha; muridae; murinae
 XX
 XX
 CL C0015;
HMG; 4.7.1.0.4.
 XX
 SZ 392 AA; 43.2 kDa (cDNA)
 XX

XX
 SC SwissProt #P35710
 XX
 FT 9 69 proline-rich region
(11/61).
 FT 27 74 serine-rich region (10/48).
 FT 183 261
HMG domain.
 FT 184 254 SM00398; HMG.
 FT 185 253 PF00505;
HMG_box.
 FT 347 384 acidic region (19/38).
 XX
 SF solution
structure similar to that of HMG1 [1];
 SF overlapping DNA-binding
specificity with SRY [2];
 SF binds to AACAAT with KD = 1 nM
[1];
 SF DNA-binding in a 1:1 stoichiometry does not affect
the protein structure,
 SF but bends the DNA [1];
 XX

CP post-meiotic germ cells; round spermatids (highest level) [2]

XX
 XX
 XX
 XX
 RN [1]; RE0004358.
 RX MEDLINE;
94359806.
 RA Connor F., Cary P. D., Read C. M., Preston N.
S., Driscoll P. C., Denny P.,
 RA Crane-Robinson C., Ashworth
A.
 RT DNA binding and bending properties of the postmeiotically
expressed
 RT Sry-related protein Sox-5
 RL Nucleic Acids
Res. 22:3339-3346 (1994).
 RN [2]; RE0002914.
 RX MEDLINE;
93010962.
 RA Denny P., Swift S., Connor F., Ashworth A.

RT An SRY-related gene expressed during spermatogenesis in the
mouse encodes a
 RT sequence-specific DNA-binding protein

RL EMBO J. 11:3705-3712 (1992).
 XX