Description:
Reading
and interpretation of statistical analyses from life science and medical
literature. Conceptual bases for using data and understanding uncertainty
when making treatment decisions about patients. Includes extensive reading
and class discussion of articles from the medical literature. Topics include:
basic concepts and tools of probability and conditional probability, independence,
two-by-two tables, Simpson's paradox, medical diagnosis, ROC curves, study
designs for medical problems, inference and hypothesis testing for RCT's,
decision analysis and decision trees, and basic survival analysis. Emphasizes
role of biostatistics, drug testing, and clinical trials in modern society.
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